TABLE 6.
Differential metabolites in MIX and CT group.
| Metabolites | VIP | P value | Fold change |
| Allo-inositol | 1.71 | 0.044 | 25.03 |
| 4-Hydroxyphenylpyruvate 1 | 1.61 | 0.016 | 15.31 |
| Elaidic acid | 1.29 | 0.001 | 4.80 |
| 3-(4-hydroxyphenyl) propionic acid | 2.09 | 0.0005 | 3.94 |
| 3-(3-hydroxyphenyl) propionic acid | 2.01 | 0.0009 | 3.25 |
| 2-Hydroxyvaleric acid | 1.91 | 0.015 | 2.55 |
| N-Carbamylglutamate 4 | 1.17 | 0.025 | 2.34 |
| Alpha-Aminoadipic acid | 2.03 | 0.0001 | 2.30 |
| Indole-3-acetamide 2 | 1.92 | 0.0004 | 2.28 |
| Inosine | 1.30 | 0.031 | 2.18 |
| Levoglucosan | 1.75 | 0.021 | 0.29 |
| Cellobiose 1 | 1.12 | 0.048 | 0.27 |
| Fucose 1 | 1.67 | 0.007 | 0.24 |
| Trans-4-hydroxy-L-proline 2 | 1.25 | 0.002 | 0.22 |
| 3-Methylglutaric Acid | 1.80 | 0.002 | 0.17 |
| N-Acetyl-beta-D-mannosamine 3 | 1.25 | 0.010 | 0.09 |
| Stearic acid | 2.47 | 0.0005 | 0.039 |
| 4-Hydroxyphenylacetic acid | 2.26 | 0.0002 | 0.036 |
| Xylose 1 | 2.17 | 0.029 | 3.09E-07 |
| Oleic acid | 2.27 | 0.023 | 2.24E-07 |
| Sorbitol | 1.72 | 0.017 | 2.10E-07 |
| Salicylaldehyde | 1.72 | 0.030 | 1.88E-07 |
| Palmitoleic acid | 2.42 | 0.005 | 1.67E-07 |
| 2-Deoxyerythritol | 2.04 | 0.003 | 1.40E-07 |
| Cis-Phytol | 2.73 | 0.0002 | 1.13E-07 |
| D-Arabitol | 2.50 | 0.012 | 8.23E-08 |
| Lyxose 1 | 1.86 | 0.028 | 6.96E-08 |
| 3-Hydroxy-3-methylglutaric acid | 2.24 | 0.035 | 4.77E-08 |
| 3,4-Dihydroxybenzoic acid | 2.49 | 5.32E-05 | 4.69E-08 |
| Citramalic acid | 1.88 | 0.009 | 3.23E-08 |
| Succinic acid | 1.81 | 0.030 | 1.48E-08 |
| Pentadecanoic acid | 2.54 | 0.0006 | 8.68E-09 |
VIP, Variable Importance in Projection; P value calculated by Student’s t test; Fold Change >2 or ≤0.3. If Fold change >1, it means that this metabolite is higher in the MIX group than that in the CT group; Vice versa.