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. 2021 Jun 11;140:111596. doi: 10.1016/j.biopha.2021.111596

Table 3.

Comparison of the inhibitory concentration of flavonoids & standard antiviral compounds.

S/N Flavonoid Inhibitory Concentration Standard Drug Inhibitory Concentration Virus Ref.
1 Silymarin 10 mg/kg/day Ribavarin+IFN 10–20 mg/kg/day HCV [30]
2 Genistein 0.4 μg/ml Acyclovir 1.6 μg/ml PI-3 [93]
3 Quercetin 0.2 μg/ml Acyclovir 1.6 μg/ml HSV-1 [93]
4 5, 7, 30, 40-tetra-O-methylquercetin 0.36 μM Oseltamivir 0.32 μM H1N1 [16]
5 Apigenin 1.6 μg/ml Acyclovir 1.6 μg/ml HSV-1 [93]
6 Fisetin 8.444 µg/ml Ribavirin 11.07 µg/ml CHIKV [27]
7 Silymarin 100 μg/ml 98% Inhibition Oseltamivir 100 μg/ml 52%- inhibition H1N1 [59]
8 Leachianone-G 1.6 μg/ml Acyclovir 1.6 μg/ml HSV-1 [64], [93]
9 Galangin 0.64 μg/ml Acyclovir 1.6 μg/ml HSV-1 [65], [93]
10 Baicalein 1.891 µg/ml Ribavirin 11.07 µg/ml CHIKV [27]
11 Q7R 0.014 μg/ml Ribavirin 4.1 μg/ml PEDV [77]
12 Silibinin 1.6 μg/ml Oseltamivir 1.6 μg/ml PI-3 [93]
13 Narinen 0.2 μg/ml Oseltamivir 1.6 μg/ml PI-3 [93]
14 Quercetin 1.69 μg/ml Acyclovir 1.6 μg/ml HSV-1 [65], [93]
15 Genistein 1.35 μg/ml Acyclovir 1.6 μg/ml HSV-1 [65], [93]
16 DHQ 75–150 mg/kg/day Ribavirin 75–150 mg/kg/day CV-B4 [73]