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. 2021 May;10(5):1386–1392. doi: 10.21037/tp-21-32

Table 2. Differential diagnosis of CGCT.

Age F to M radio Predilection site Multiple radio Histopathology Immunohistochemistry Prognosis
CGCT Neonate or newborn 9-10:1 Alveolar ridge 10% of case Sheets and nests of large polygonal cells with demarcated cell membrane and granular cytoplasm. The nuclei are typically small, uniform, and pale staining, without evidence of mitotic activity S100(-) No recurrence and malignant transfer
GCT (2,16) 30 to 60 years old 2:1 Tongue 13% of case Polygonal and abundant eosinophilic granular cytoplasm. The nuclei may be centrally or eccentrically located and are typically uniform, small, round, and pale-staining S100(+); CD57(+); SOX10(+); CD68(+) Rare recurrence and malignant transfer