Table 3.

Area under the receiver-operating characteristic curve (AUC) of biomarkers for predicting hemorrhagic transformation in derivation and validation cohorts.

	Derivation cohort (n = 1,207)		Validation cohort (n = 288)
	AUC (95% CI)	P-value	AUC (95% CI)	P-value
Platelets (× 109/L)	0.60 (0.56–0.65)	<0.001	0.59 (0.47–0.72)	0.157
Neutrophil-to-lymphocyte ratio	0.62 (0.58–0.67)	<0.001	0.73 (0.62–0.83)	<0.001<
High-density lipoprotein cholesterol (mmol/L)	0.57 (0.52–0.62)	<0.003	0.61 (0.49–0.74)	0.081
All three biomarkers	0.64 (0.60–0.69)	<0.001	0.70 (0.58–0.82)	<0.001<