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. 2021 May 28;15:647266. doi: 10.3389/fnins.2021.647266

FIGURE 2.

FIGURE 2

Tyrosine hydroxylase (TH) content and α-synuclein level. (A) Visualization of TH content and α-synuclein immunohistochemical staining in corpus striatum (STR) and substantia nigra (SN) of subject mice. Less TH content and higher level of α-synuclein were detectable in the A53T group. (B,C) When quantified, optical density (OD) and expression of α-synuclein were higher, and OD and expression of TH-positive cells were decreased in the A53T group (*P < 0.05; **P < 0.01). Following 2-week Dl-3-n-butylphthalide (NBP) application, the level of α-synuclein was lower and TH-positive cells were increased significantly (#P < 0.05). All data were expressed as mean ± SD.