Table 6.
DMM overlap with down-regulated DEGs.
| Gene name | Gene symbol | gene ontology terms of biological processes (selected) | mRNA regulation Log2-fold change |
|---|---|---|---|
| SPARC like 1 | SPARCL1 | cellular protein metabolic process | −1.92692 |
| transmembrane protein 30B | TMEM30B | aminophospholipid transport | −1.57251 |
| dual specificity phosphatase 1 | DUSP1 | inactivation of MAPK activity | −1.56709 |
| zinc finger and BTB domain containing 10] | ZBTB10 | nucleoplasm | −1.40601 |
| fibrinogen like 2 | FGL2 | immunoglobulin production involved in immunoglobulin mediated immune response | −1.39772 |
| protocadherin 7 | PCDH7 | cell adhesion | −1.35683 |
| Kruppel like factor 9 | KLF9 | regulation of transcription by RNA polymerase II | −1.31683 |
| fibulin 5 | FBLN5 | extracellular matrix organization | −1.24061 |
| kinesin family member 5B | KIF5B | cytoplasm organization | −1.06699 |
| purine rich element binding protein A | PURA | DNA replication initiation | −1.04003 |
DMM, differentially methylated N6-methyladenosine; DEGs, differential expressed genes. Differentially methylated N6-methyladenosine overlap with down-regulated differential expressed genes. Multiple genes are associated with elastic fiber assembly and immune response.