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HSAV adjusts PKCζ-mediated oxidative stress signal pathway in vitro and in vivo. The expression levels of sirtuin 1 (Sirt1), Ketch-like ECH-associated protein 1 (Keap1), nuclear factor E2-related factor 2 (Nrf2), NAD(P)H quinone dehydrogenase 1 (NQO1), and glutathione 5-transferase (GST) in HUVECs (A) and rat thoracic aorta (B) by Western blot assay (n = 3). Data are presented as the mean ± SD. *p < 0.05, **p < 0.01, compared with the model group.
