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Schematic diagram illustrating potential pathways associated with cell death in compound 3K-treated SK-OV-3 cells. Compound 3K-induced cell death is associated with the Akt/AMPK/mTOR signaling pathway. Compound 3K induces phosphorylation of AMPK at Thr172 and reduces the phosphorylation of Akt. These molecular changes cause the suppression of mTOR signaling, thereby regulating autophagy and apoptosis.
