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A proposed mode for EPB41L4A-AS2-mediated the regulation of NPC metastasis. In the nucleus, EPB41L4A-AS2 relies on binding YBX1 to enhance the stability of snail mRNA to reduce the expression of E-cadherin and promote EMT. In the cytoplasm, EPB41L4A-AS2 suppresses NPC metastasis via mir-107-LATS2 axis at the post-transcriptional level.
