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. 2021 May 11;17(8):1963–1978. doi: 10.7150/ijbs.55557

Figure 8.

Figure 8

EPB41L4A-AS2 might serve as a ceRNA, sponging miR-107, inhibited the invasion and migration of NPC cells. (A) The expression of miR-107 in different treatment cells was detected by qRT-PCR. (B)The binding sequences between EPB41L4A-AS2 and miR-107. (C)The results of luciferase reporter showed that miR-107 directly targets EPB41L4A-AS2. (D) RIP assays exhibited that miR-107 overexpression significantly increased the enrichment of EPB41L4A-AS2 in the anti-Ago2 antibody. (E) The wound healing assays indicated that EPB41L4A-AS2 repressed the cell migration via targeting miR-107. (F and G) The transwell assays showed that EPB41L4A-AS2 inhibited the invasion and migration of NPC cells through repression of miR-107. *P < 0.05 and **P < 0.01.