Figure 5.

PPD prevents the risk of spontaneous abortion of EMs mice. (A) After 28 days of treatment with Ctrl (5 % DMSO, every days), PPD (45 mg/kg, every 4 days), and GnRHa (0.5 µg, every day), these female EMs mice were mated with healthy adult male mice. (B-D) The pregnancy rates, number of embryos implanted and the embryo absorption rate of the control group, the PPD group, and the GnRHa group at the gestation of day 13.5 were quantified in (C&D), and the absorption sites were indicated by the red triangle (n=16). Mean ± SEM, NS, no significant difference, **p<0.01, ***p<0.001.