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. 2021 Feb 24;44(6):zsab046. doi: 10.1093/sleep/zsab046

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Figure 1. — Experimental study design. LepR^b-deficient db/db mice were randomly transfected with Ad-LepR^b or Ad-mCherry in the dorsomedial hypothalamus (DMH). Mice received intracerebroventricular (ICV) infusions of either PBS or leptin in a cross-over design and underwent polysomnography at days 9 and 13 after injection. LepR^b: long isoform of leptin receptor.