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Energy expenditure and motor activity during the light phase in db/db mice infected with Ad-LepRb-GFP or Ad-mCherry. Each line represents individual mice; mean values ± standard errors are shown. There were no changes in (A) total oxygen consumption (VO2), (B) total carbon dioxide production (VCO2), (C) respiratory exchange ratio (RER) and (D) total motor activity between the Ad-LepRb and Ad-mCherry groups with either PBS or leptin infusions. *p < 0.05.
