Table 1.
Characteristics of age, weight, temperature, and food intake for db/db mice transfected with either Ad-mCherry or Ad-LepRb and infused with PBS or leptin ICV
| Age, weeks | Weight, g | Temperature, °C | Food intake, g | ||||||
|---|---|---|---|---|---|---|---|---|---|
| n | Mean ± SE | Range | Mean ± SE | Range | Mean ± SE | Range | Mean ± SE | Range | |
| Ad-mCherry | |||||||||
| PBS | 12 | 15.9 ± 0.0 | 15.0–17.0 | 47.4 ± 0.9 | 39.4–50.6 | 36.1 ± 0.3 | 34.6–37.5 | 3.0 ± 0.5 | 2.1–5.9 |
| Leptin | 12 | 16.0 ± 0.1 | 15.0–17.1 | 46.9 ± 1.0 | 39.9–51.5 | 35.4 ± 0.2 | 34.4–36.6 | 3.0 ± 0.4 | 2.3–5.2 |
| Ad-LepR b | |||||||||
| PBS | 14 | 15.7 ± 0.1 | 14.0–17.4 | 49.4 ± 1.3 | 35.7–55.4 | 35.8 ± 0.3 | 33.3–37.8 | 3.2 ± 0.2 | 1.6–4.5 |
| Leptin | 14 | 15.7 ± 0.1 | 14.0–17.0 | 49.8 ± 1.2 | 36.9–56.0 | 36.3 ± 0.2* | 35.1–38.2 | 2.5 ± 0.3*** | 1.6–3.8 |
Weight was recorded prior to sleep recording. Rectal temperature was averaged between beginning and end of sleep recording. Food intake was measured for 24 h post leptin or PBS treatment. Values presented as mean values ± standard error and range.
ICV, intracerebroventricular.
*p < 0.05; ***p < 0.001.