Table 1.

Summary of weight loss and metabolic disease outcomes for various endobariatric interventions.

Procedure	TBWL at 12 months	HbA1c (%)	HOMA-IR	ALT (IU/l)	Improved hepatic steatosis	Improved liver fibrosis
Intragastric balloon15–20	7.6–9.2%	−1.2%	N/A	−52	+	+
Endoscopic sleeve gastroplasty21–29	16.5%	−0.4%	−3.8	−5.0	+	+
Aspiration therapy30–32	14.2%	−0.3%	N/A	−15.5	N/A	N/A
Duodenal mucosal resurfacing33,34	2–3% (at 6 months)	−1.0%	−3.3	−10.0	N/A	N/A
Duodenal-jejunal bypass liner35–38	14.6%	−1.3%	−4.6	N/A	N/A	N/A
Endoluminal magnetic partial jejunal diversion 39	14.6%	−1.9%	N/A	N/A	N/A	N/A

ALT, alanine transaminase; HOMA-IR, Homeostatic Model Assessment for Insulin Resistance; TBWL, total body weight loss.

All values reported as mean difference.