Figure 4.

Inhibition of miR-132 partially reverses the effect of circVAPA knockdown in oral cancer cells. a: RT-qPCR was used to detect the expression of miR-132 in cells transfected with a negative control (NC) or miR-132 inhibitor. ***P < 0.001 compared with NC inhibitor. b: The cell counting kit-8 method was used to detect the cell viability at 0, 24, 48 and 72 hours in different groups indicated by the optical density (OD). ***P < 0.001. c: The clone formation ability of Cal-27 cells in different groups was detected by clone formation assays. **P < 0.01 and ***P < 0.001. d: Transwell assay (without Matrigel) was used to detect the migration ability of Cal-27 cells in different groups. *P < 0.05, ***P < 0.001. e: Transwell assay (with Matrigel) was used to detect the invasion ability of Cal-27 cells in different groups. **P < 0.01 and ***P < 0.001