Figure 5.

Extent of myxoid stroma area to be judged as in the immature DR category. For the minimum amount of myxoid stroma to be judged as immature, the microscopic field of a ×40 objective lens is used as a yardstick. (A) Although there is an area with stromal mucin, as circled with a black dotted line, it does not completely fill the field of a ×40 objective lens, thereby does not meet the criteria to place it in the immature category; (B–D) Increased stromal mucin forms the area of myxoid stroma, which fully occupies the field of a ×40 objective lens with various proportions of stromal mucin-to-collagen fibers. These DR lesions are classified in the immature category. (A–D) Microscopic fields of a ×40 objective lens (field number, 20; H&E staining).