Table 3. Diagnostic performances of CT imaging features for differentiating PNENs G3 from PNENs G1/G2.
| CT features | Sensitivity (%) | Specificity (%) | AUC | 95% CI |
| The cut-off point of tumor size (mm), arterial enhancement degree (HU), portal enhancement degree (HU), arterial enhancement ratio, and portal enhancement ratio are 23.6, 73.12, 71.69, 1.06, and 0.98, respectively. CT: computed tomography; PNENs: pancreatic neuroendocrine neoplasms; AUC: area under the curve; CI: confidence interval; HU: Hounsfield units. | ||||
| Tumor size (mm) | 100.0 | 49.4 | 0.747 | 0.692–0.802 |
| Shape | 100.0 | 65.4 | 0.827 | 0.775–0.879 |
| Margin | 92.3 | 88.9 | 0.906 | 0.823–0.989 |
| Heterogeneity | 84.6 | 50.6 | 0.676 | 0.560–0.792 |
| Intratumoral blood vessels | 38.5 | 86.4 | 0.624 | 0.482–0.767 |
| Vascular invasion | 53.9 | 85.2 | 0.695 | 0.549–0.841 |
| Arterial enhancement pattern | 84.6 | 81.5 | 0.831 | 0.720–0.941 |
| Portal enhancement pattern | 84.6 | 67.9 | 0.763 | 0.648–0.877 |
| Arterial enhancement degree (HU) | 69.2 | 92.6 | 0.809 | 0.675–0.943 |
| Portal enhancement degree (HU) | 69.2 | 93.8 | 0.815 | 0.682–0.948 |
| Arterial enhancement ratio | 84.6 | 80.3 | 0.824 | 0.713–0.935 |
| Portal enhancement ratio | 84.6 | 86.4 | 0.855 | 0.746–0.964 |
| Common bile duct dilatation | 38.5 | 96.3 | 0.674 | 0.535–0.813 |
| Lymph node metastases | 61.5 | 91.4 | 0.765 | 0.623–0.906 |
| Liver metastases | 30.8 | 96.3 | 0.635 | 0.503–0.768 |