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. 2021 Jan 29;35(3):216–227. doi: 10.7555/JBR.35.20200154

Figure 2.

Figure 2

SARS-CoV-2 encoded candidate miRNAs targeting at the 3′-UTR of genes.

A: The GO functions enriched by the putative virus-miRNAs regulated genes. GO IDs with P-value <0.001 were labeled, and the size of bubbles is proportion to the number of genes annotated to the corresponding GO terms. B: Diagram examples of the binding of the putative virus-encoded miRNAs with 3′-UTR. C: The expression of the target genes of putative virus-encoded miRNAs in Vero E6 cells infected with SARS-CoV-2 ( n=3, data are presented as mean±SD). D: The expression of genes targeted by MR147-3p in BEAS-2B cell transfected with MR147-3p (n=3, data are presented as mean±SD). *P<0.05,**P<0.01, and****P<0.0001. GO: Gene Ontology.