Supplementary Table 4. Results of the univariate and the multivariate Cox analyses for the risk factors associated with disease progression (i.e., a ≥ 30% estimated glomerular filtration rate decline or end-stage renal disease) among the entire study population ( n = 112) .
| Variables | Univariate Analysis | Multivariate Analysis | P -Value for interaction | ||
|---|---|---|---|---|---|
| Hazard Ratio (95% CI) | P -Value | Hazard Ratio (95% CI) | P -Value | ||
| Age (1 year increase) | 1.04 (1.00–1.07) | 0.0343 | 0.98 (0.91–1.05) | 0.5249 | 0.0423 |
| Men (vs. women) | 1.27 (0.70–2.38) | 0.4335 | 0.83 (0.37–1.83) | 0.6505 | 0.3245 |
| eGFR (10 mL/min/1.73 m 2 increase) | 0.64 (0.53–0.76) | ＜0.0001 | 0.70 (0.56–0.87) | 0.0010 | - |
| UACR (10 mg/g Cre increase) | 1.01 (1.01–1.02) | ＜0.0001 | 1.01 (1.00–1.01) | 0.0065 | - |
| Serum Albumin (1 g/dL increase) | 0.05 (0.02–0.18) | ＜0.0001 | 0.21 (0.04–1.02) | 0.0526 | - |
| Hypertriglyceridemia (vs. no) | 2.24 (1.06–5.48) | 0.0334 | 1.48 (0.57–3.91) | 0.4178 | - |
| Low HDL cholesterol (vs. no) | 1.65 (0.91–3.06) | 0.0981 | 1.47 (0.57–3.89) | 0.4322 | - |
| Antidyslipidemic agents (vs. no) | 1.31 (0.72–2.38) | 0.3689 | - | - | - |
| Max IMT (1 mm increase) | 1.42 (1.07–1.83) | 0.0151 | 1.49 (1.02–2.12) | 0.0394 | 0.0770 |
Variables with a P -value ＜0.1 in the univariate model, as well as age, sex, eGFR, and interaction terms of interest (variables with a P -Value for interaction ＜0.1 in the Table 2 ＊ age ≥ 65 years), were included in the multivariate model. Abbreviations: n , number; CI, confidence interval; P , calculated probability; vs., versus; eGFR, estimated glomerular filtration rate; UACR, urine albumin-to-creatinine ratio; Cre, creatinine; HDL, high-density lipoprotein; Max IMT, maximum measurable intima-media thickness in the entire scanned common carotid arteries, carotid bulbs, and internal carotid arteries.