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. Author manuscript; available in PMC: 2021 Jun 11.
Published in final edited form as: Neurobiol Learn Mem. 2019 Aug 5;164:107064. doi: 10.1016/j.nlm.2019.107064

Fig. 3.

Fig. 3.

Age-dependent redox regulation of the NMDA receptor component of synaptic transmission. The top panels illustrates the response under control conditions (black line) for aged (left) and young (right) and following application of the reducing agent, DTT (gray line). DTT induces a large increase in the NMDA receptor response in older animals. The bottom panel illustrates the response under control conditions (black line) for aged (left) and young (right) and following application of the oxidizing agents, X/XO (gray line). Oxidizing conditions decrease the NMDA receptor response in young animals. Figure adapted from Bodhinathan et al. (2010b).