Table 7.

Multivariate analyses regarding CSS in patients with ESCC.

		HR (95% CI)	P-value
Model 1	CRP (mg/L, > 10.0 vs. ≤ 10.0)	1.532 (1.102-2.128)	0.011
	NPS (model 1)
	1 vs. 0	1.978 (1.250-3.130)	0.004
	2 vs. 0	2.903 (1.803-4.675)	<0.001
	TNM stage
	II vs. I	1.620 (1.087-2.416)	0.018
	III vs. I	2.196 (1.494-3.227)	<0.001
Model 2	CRP (mg/L, > 10.0 vs. ≤ 10.0)	1.618 (1.171-2.235)	0.004
	TNM stage
	II vs. I	1.643 (1.101-2.451)	0.015
	III vs. I	2.269 (1.544-3.334)	<0.001
	NPS (model 2)
	1 vs. 0	3.072 (1.480-6.380)	0.003
	2 vs. 0	5.239 (2.536-10.825)	<0.001

ESCC, esophageal squamous cell carcinoma; NPS, Naples prognostic score; CRP, C-reactive protein; TNM, tumor node metastasis; CI, confidence interval; HR, hazard ratio; CSS, cancer-specific survival. Model 1: The cut-off values according to the previous published studies. Model 2: The cut-off values according to the ROC curves in the current study.