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. 2021 May 28;9:644380. doi: 10.3389/fcell.2021.644380

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Copyright © 2021 Wang, Li, Cui, Cui, Chen and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Identification of chondrocytes using immunocytochemical staining of collagen II (100×). (B) The expression level of IL-1β after chondrocytes were induced by IL-1β. *P < 0.05 vs. control group. n = 3. (C) The expression level of IL-6 after chondrocytes were induced by IL-1β. *P < 0.05 vs. control group. n = 3. (D) PKH67-labeled exosomes could be taken up by chondrocytes induced by IL-1β after co-culture.