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. 2021 Jun 11;9:26. doi: 10.1186/s40170-021-00262-9

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Eleven mice were injected with ring-¹³C₆-Phe and three additional mice were injected with normal saline into the lateral tail vein when the tumors reached 1000 mm³. The tracer-infused mice were subsequently sacrificed at 10 min (n = 4), 30 min (n = 3), and 60 min (n = 4) after injection, and sham-treated mice were sacrificed after 10 min