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Interaction between macroglia and microglia in glaucoma. Microglia and macroglia are involved in the progression of neuroinflammation in glaucoma, including the inflammatory cytokine, TLR, TSPO, and complement pathways. In addition, microglia prompt macroglia to produce neurotrophic factors and help regulate synaptic activity, whereas macroglia provide microglia with the physical scaffold support and energy required for activities.
