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. 2021 May 28;12:635072. doi: 10.3389/fimmu.2021.635072

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Copyright © 2021 Bagavant, Araszkiewicz, Ingram, Cizio, Merrill, Arriens, Guthridge, James and Deshmukh

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IgG anti-Eg (A) and IgA anti-Eg (B) titers in sera from healthy controls and lupus patients. Antibody titers are plotted as units/mL and the lines show median ± interquartile ranges. Correlation between IgG and IgA anti-Eg titers in lupus patients (C). Each data point represents one serum sample and the number of samples studied are shown in parentheses. Antibody levels were compared by Mann-Whitney test and the correlation coefficient was determined by Pearson’s method. ns, not significant.