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. 2021 May 28;12:680896. doi: 10.3389/fneur.2021.680896

Table 3.

Changes in regional homogeneity in patients with migraine without aura and healthy controls during the study period.

(A) Difference in ReHo between MwoA and HCs
Contrast Brain region MNI (x, y, z) T-value Voxels
PM < HC Right cerebellum 18 −60 −42 4.4607 131
Left cerebellum −18 −63 −42 4.9429 102
(B) Changes in ReHo in different stages of treatment
Contrast Brain region MNI (x, y, z) F-value Voxels
PMa-PMb-PMc Left cerebellum −9 −36 −30 3.805 20
Left angular gyrus −60 −63 27 3.7857 23
(B1) Changes in ReHo in different stages (post-hoc analysis)
Contrast Brain region MNI (x, y, z) T-value Voxels
PMb > PMa Left cerebellum −12 −33 −33 4.7578 20
(B2) Changes in ReHo in different stages (post-hoc analysis)
Contrast Brain region MNI (x, y, z) T-value Voxels
PMc > PMa Left angular gyrus −57 −57 24 4.848 23
(B3) Changes in ReHo in different stages (post-hoc analysis)
Contrast Brain region MNI (x, y, z) T-value Voxels
PMc > PMb Left angular gyrus −60 −63 27 3.9827 20

(A) Comparison of ReHo between patients with MwoA and HCs. (B) Changes in ReHo in different periods of acupuncture treatment (P < 0.001, GRF, cluster P < 0.05, cluster >20). (B1) Changes in ReHo between before and after first acupuncture session (FWE, P < 0.05). (B2) Changes in ReHo between before and after acupuncture (FWE, P < 0.05). (B3) Changes in ReHo between after first acupuncture session and after 12th acupuncture session (FWE, P < 0.05). FWE, family-wise error; HCs, healthy controls; MwoA, migraine without aura; ReHo, regional homogeneity; PM, patients with migraine; PMa, before acupuncture; PMb, after first acupuncture session; PMc, after 12th acupuncture session.