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. 2021 Jun 10;26(23):2000052. doi: 10.2807/1560-7917.ES.2021.26.23.2000052

Table 3. Inter-rater reliability of 3CAT, WHOCAT and QUANT, measured with kappa, weighted kappa, adjusted weighted kappa, percentage agreement and/or the intraclass correlation coefficient mortality review of the contribution of healthcare-associated infections to death, 11 EU countries, April 2017–February 2018 (n = 291).

3CAT n Simple kappa (95% CI) Weighted kappa (95% CI) Weighted kappa, adjusted for hospitala (95% CI) Agreement (%)
Overall Definitely Possibly No
Overall 291 0.62 (0.54–0.70) 0.68 (0.61–0.75) 0.63 (0.55–0.71) 76 84 73 65
BSI 87 0.56 (0.41–0.72) 0.60 (0.46–0.76) 0.38 (0.20–0.56) 76 81 73 44
Pneumonia 113 0.66 (0.55–0.78) 0.72 (0.62–0.82) 0.82 (0.74–0.90) 78 86 74 73
CDI 71 0.49 (0.32–0.67) 0.57 (0.41–0.73) 0.55 (0.40–0.70) 69 74 69 58
SSI 20 0.87 (0.65–1.00) 0.88 (0.70–1.00) Not calculated 95 100 89 0b
WHOCAT n Simple kappa (95% CI) Weighted kappa (95% CI) Weighted kappa, adjusted for hospitala (95% CI) Agreement (%)
Overall Sole cause Causal sequence Contributory cause No
Overall 288 0.58 (0.51–0.66) 0.65 (0.58–0.73) 0.75 (0.71–0.80) 74 62 85 51 69
BSI 86 0.56 (0.41–0.71) 0.60 (0.43–0.77) 0.63 (0.55–0.71) 75 70 86 53 46
Pneumonia 110 0.66 (0.54–0.78) 0.72 (0.60–0.83) 0.89 (0.83–0.96) 80 0 a 91 48 77
CDI 68 0.47 (0.30–0.64) 0.52 (0.34–0.70) 0.56 (0.46–0.66) 65 36 76 53 62
SSI 17 0.56 (0.22–0.90) 0.63 (0.29–0.97) Not calculated 72 83 80 0 a 0b
QUANT n ICC (95% CI) for absolute agreement
Overall 289 0.76 (0.71–0.81)
BSI 87 0.75 (0.62–0.83)
Pneumonia 111 0.85 (0.79–0.90)
CDI 71 0.54 (0.35–0.69)
SSI 20 0.71 (0.41–0.87)

3CAT: three-category mortality review measure; CI: confidence interval; BSI: bloodstream infection; CDI: Clostridioides difficile infection; EU: European Union; ICC: intraclass correlation coefficient; QUANT: quantitative Likert scale from 0 to 10; SSI: surgical site infection; WHOCAT: World Health Organization death certification based measure.

a Excluding hospitals with fewer than six cases.

b Zero cases with agreement, one case in denominator; cases where one of the ratings was missing or ‘unknown’ were excluded.

Percentages are presented in italics.