Table 2.
Demographic and echocardiographic parameters between bileaflet and single-leaflet prolapse (N = 253)
| Single-leaflet prolapse (n = 105) | Bileaflet prolapse (n = 148) | P value | |
|---|---|---|---|
| Age, years | 66 ± 15 | 60 ± 16 | .003 |
| Sex, male | 39 (37) | 52 (35) | .74 |
| Hypertension | 41 (39) | 42 (29) | .07 |
| Diabetes | 7 (7) | 10 (7) | .98 |
| CAD | 20 (19) | 23 (16) | .45 |
| Creatinine, mg/dL | 0.90 ± 0.16 | 0.87 ± 0.18 | .15 |
| Body surface area, m2 | 1.81 ± 0.20 | 1.79 ± 0.22 | .35 |
| Body mass index, kg/ m2 | 24.8 ± 4.5 | 24.0 ± 4.6 | .16 |
| Atrial fibrillation | 4 (4) | 12 (8) | .15 |
| Presence of PVCs | 25 (24) | 35 (24) | .97 |
| SBP, mm Hg | 123 ± 19 | 119 ± 18 | .06 |
| Diastolic blood pressure, mm Hg | 72 ± 10 | 69 ± 9 | .019 |
| Heart rate beats/minute | 67 ± 12 | 68 ± 13 | .54 |
| MAD | 22 (21) | 69 (47) | <.0001 |
| MR EROA, mm2 | 11.5 ± 3.5 | 12.6 ± 3.7 | .023 |
| MR Rvol, mL/beat | 18.9 ± 5.8 | 17.1 ± 6.0 | .016 |
| LVEF, % | 62 ± 6 | 62 ± 5 | .82 |
| LVEDD, mm | 49 ± 5 | 49 ± 4 | .68 |
| LVEDD index, mm/m2 | 27.3 ± 3.2 | 27.6 ± 2.9 | .51 |
| LVESD, mm | 31 ± 5 | 31 ± 4 | .99 |
| LVESD index, mm/m2 | 17.4 ± 2.7 | 17.7 ± 2.3 | .44 |
| LVMi, g/m2 | 97 ± 21 | 91 ± 19 | .028 |
| Relative wall thickness | 0.39 ± 0.07 | 0.38 ± 0.06 | .10 |
| eLVH | 22 (21) | 19 (13) | .08 |
| LA volume index, mL/ m2 (n = 567) | 38 ± 20 | 38 ± 13 | .80 |
| E/A ratio (n = 550) | 1.08 ± 0.42 | 1.17 ± 0.46 | .16 |
| E/e’ ratio (n = 584) | 11 ± 5 | 11 ± 4 | .43 |
| Mild AR* | 15 (14) | 15 (10) | .37 |
| Mild-to-moderate TR† | 16 (15) | 16 (11) | .29 |
| AV peak velocity, m/sec | 1.38 ± 0.24 | 1.28 ± 0.24 | .001 |
AR, Aortic regurgitation; AV, aortic valve; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic dimension; TR, tricuspid regurgitation.
Data are expressed as mean ± SD or n (%).
*
The remainder has trivial or no AR.
†
The remainder has no, trivial, or mild TR.