Table 2.
PIK3CA variants allele frequencies in tissues and isolated cells
| Disease | Sample type | Mutation | VAF (%) |
|---|---|---|---|
| CLVM | Tissue | p.His1047Arg | 5 |
| CD31-positive cells (EC) | p.His1047Arg | 47 | |
| CD31-negative cells | p.His1047Arg | 0 | |
| LM | Tissue | p.Glu542Lys | 11 |
| Unselected cells | p.Glu542Lys | 4 | |
| CD34-positive cells (BEC) | p.Glu542Lys | 17 | |
| CD31-positive and CD34-negative cells (LEC) | p.Glu542Lys | 32 | |
| CD31- and CD34-negative cells | p.Glu542Lys | 0 | |
| Fibroblasts | p.Glu542Lys | 0 |
VAF, variant allele frequency; EC, endothelial cell; BEC, blood endothelial cell; LEC, lymphatic endothelial cell