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Differential expression of immunohistochemical biomarkers in eCCA with respect to iCCA.
| eCCA > iCCA | eCCA = iCCA | eCCA < iCCA |
|---|---|---|
| Akt2 | Aurora-A | Aurora-B |
| Annexin II | β-catenin | bcl-2 |
| c-erbB-2 | Bax | EGFR |
| CD10 | CK7 | Filamin A |
| CDX2 | CK8 | Galectin-1 |
| CK20 | CK18 | p16 |
| MUC1 | CK19 | p27 |
| MUC5AC | Cyclin D1 | SMAD-4 |
| p53 | COX-2 | VEGF-A |
| S100P | D10 | |
| E-cadherin | ||
| Fas | ||
| hENT1 | ||
| Mdm-2 | ||
| Metallothionein | ||
| MUC6 | ||
| p21 | ||
| S100A4 | ||
| TNF-α | ||
| VEGF | ||
| Vimentin |
