TABLE 1.
Summary of genes downregulated in the cochlea of Meis2 mutants.
| Gene (MGI reference) | Fold Downregulation | Expression pattern |
| Acidic nuclear phosphoprotein 32 family (5332981) | 4.1x | Mesenchyme |
| THUMP domain containing 3 (1277973) | 3.7x | Otic capsule |
| Itchy, E3 ubiquitin protein ligase (4825634) | 3.4x | Ganglion |
| Zinc finger protein 788 (1914857) | 3.1x | Ganglion |
| Neurofilament, light polypeptide (97313) | 3.1x | Ganglion |
| Trafficking protein particle complex 4 (4480575) | 2.9x | Ganglion |
| Centrosome/spindle pole associated protein (2681832) | 2.7x | Ganglion |
| FK506 binding protein 3 (5335642) | 2.7x | Mesenchyme |
| Chromodomain helicase DNA binding protein 7 (2444748) | 2.6x | Cochlear duct, ganglion and mesenchyme |
| Craniofacial development protein 1 (1344403) | 2.4x | Cochlear duct and ganglion |
| Formin binding protein 1-like (1925642) | 2.4x | Ganglion |
| Ephrin A1 (103236) | 2.4x | Cochlear duct |
| Thymidylate synthase (98878) | 2x | Mesenchyme |
The localization of the genes within the cochlea is annotated according to Mouse Genome Informatics (MGI) using RNA in situ hybridization. The table shows a list of genes which are expressed in the cochlea and down regulated by twofold or higher in Meis2 mutants according to the results obtained by the microarrays.