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Schematic diagram of intracellular signal transduction pathways related to wound healing involving SDF-1/CXCR4. Various stimuli in vivo and in vitro will affect the expression of CXCR4 on the cell membrane, regulate the CXCR4 signaling pathway and participate in various processes of wound repair including proliferation, differentiation, and migration etc. BL-8040: antagonist of CXCR4; FIR, Far-infrared radiation; VEGF, vascular growth factor; EGF, epidermal growth factor.
