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. 2021 May 28;8:680397. doi: 10.3389/fmolb.2021.680397

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Copyright © 2021 Altaf, Wu and Kasim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Domain structure of recombinant tissue-type plasminogen activator (rtPA). It consists of fibronectin type I domain, an epidermal growth factor domain, as well as kringle 1, kringle 2 and serine protease domains.