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Mendelian Randomization for the causal effect of CpG sites on CHD risk
| CpG | CHR | POSITION | Nearby Gene | mQTL SNPa | POSITION | p.MR1b | p.MR2c |
|---|---|---|---|---|---|---|---|
| cg00598125 | 6 | 32,555,411 | HLA-DRB1 | kgp10246631 | 32,504,218 | 0.53 | 3.27e-05 |
| kgp3830872 | 32,519,391 | ||||||
| kgp11968335 | 32,554,197 | ||||||
| kgp12271317 | 32,561,327 | ||||||
| rs9270894 | 32,571,872 | ||||||
| kgp132887 | 32,578,970 | ||||||
| kgp7143578 | 32,589,959 |
a 7 mQTL SNPs of cg00598125 were used as instrumental SNPs in Mendelian randomization
b MR analysis in CHD GWAS Phase 1
c MR analysis in CHD GWAS Phase 2
