Table 1.
Clinical course of laboratory results and treatment.
| Laboratory value or treatment dose | Pretreatment | After 6 days | After 2 weeks | After 3 weeks | After 4 weeks | After 2 months | After 6 months |
|---|---|---|---|---|---|---|---|
| ALT (U/L; normal range, <30) | 1323 | 455 | 175 | 318 | 151 | 41 | 22 |
| GGT (U/L; <40) | 136 | 200 | 239 | 345 | 194 | 29 | 12 |
| T Bil (mg/dL; <1.2) | 6.5 | 3.4 | 1.5 | 1.4 | 0.9 | 0.6 | 0.7 |
| D Bil (mg/dL; <0.4) | 4.0 | 1.9 | 0.4 | 0.5 | 0.1 | 0.1 | 0.1 |
| PT-INR (0.75 to 1.15) | 1.73 | 1.15 | 0.96 | 0.98 | 0.9 | 0.99 | n.d. |
| IgG (mg/dL; 500 to 1280) | 2098 | n.d. | 1079 | n.d. | n.d. | 970 | 1170 |
| mPSL (mg/kg/day) | 30 × 3 days | ||||||
| PSL (mg/kg/day) | 1.5 | 1.5 | 1.2 | 1.2 | 0.4 | 0.15 | |
| AZA (mg/kg/day) | - | - | - | 1.2 | 1.2 | 2.0 | |
ALT, alanine aminotransferase; GGT, gamma glutamyl-transferase; T Bil, total bilirubin; D Bil, direct bilirubin; PT-INR, prothrombin time-international normalized ratio; n.d., not done; IgG, immunoglobulin G; mPSL, methylprednisolone; PSL, prednisolone; AZA, azathioprine; -, no treatment.