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. 2021 May 28;12:661072. doi: 10.3389/fphar.2021.661072

FIGURE 4.

FIGURE 4

Autophagy inhibitor 3-MA attenuates the anti-inflammatory and anti-cartilage degradation effects of ROF in chondrocytes. (A) Western blots and (B) quantitative analysis of iNOS and COX-2 in each group. (C) Western blots and (D) quantitative analysis of collagen Ⅱ, MMP13, and ADAMTS5 in each group. GAPDH was employed as the internal control (n = 3). #p < 0.05 vs. control group; *p < 0.05 and **p < 0.01 vs. IL-1β group;$ p < 0.05 vs. IL-1β + ROF (20 μM) group.