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. 2021 May 28;12:582447. doi: 10.3389/fphar.2021.582447

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Copyright © 2021 Wang, Zheng, Chen, Jiang, Huang, Jiang, Hu, Huang, Liu, Gong, Feng, Xiao, Li and Xiao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The analysis of tumor response between two groups 3a.The analysis of ORR between two groups. The pooled result showed a significant improvement in ORR in the Aidi and GP combination group compared to that in the control group (OR = 1.82, 95% CI [1.62 to 2.04], p < 0.00001). Note: GP, Gemcitabine, and cisplatin; ORR, objective response rate. 3b. The analysis of DCR between two groups. The pooled result showed a significant improvement in DCR in the Aidi and GP combination group compared to that in the control group (OR = 2.29, 95% CI [1.97 to 2.67], p < 0.00001). Note: GP, Gemcitabine, and cisplatin; DCR, disease control rate.