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Downregulation of PIP enhanced PDLSCs osteogenic differentiation. (A) ALP staining of PDLSCs after osteogenic induction for 14 days. (B) ALP activity assay of PDLSCs after osteogenic induction for 14 days. (C) Alizarin Red staining of PDLSCs after osteogenic induction for 21 days. (D) The protein level of ALP and COL1 in shNC and shPIP PDLSCs after 14 days of induction. (E) The quantitative analysis of western blot. * P<0.05.
