TABLE 2.

Targeting channels of compounds.

Compound	Channel	Mechanism	References
SKF96365	SOCE	Inhibitor	Iwamuro et al. (1999)
	RMCE	Inhibitor	Merritt et al. (1990); Cabello and Schilling (1993)
	TRP channels	Inhibitor	Bennett et al. (2001)
	CCE	Inhibitor	Wu et al. (1999)
2-APB	SOCE IP3R channel TRP channels	Activator-Low concentration	Peinelt et al. (2008)
		Inhibitor-high concentration inhibitor	Peinelt et al. (2008)
		Activator-TRPV1 TRPV2 TRPV3 TRPM6 TRPC3	Maruyama et al. (1997)
		Inhibitor-TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TRPM2 TRPM3 TRPM7 TRPM8 TRPV3 TRPV6	Ma et al. (2003); Chung et al. (2004); Hu et al. (2004); Li et al. (2006); Colton and Zhu (2007)
			Hu et al. (2004); Poburko et al. (2004); Li et al. (2006); Colton and Zhu (2007); Chokshi et al. (2012)
DPB-162AE	SOCE	Specific inhibitor	Goto et al. (2010); Hendron et al. (2014); Bittremieux et al. (2017)
DPB-163AE	SOCE	Activator-Low concentration	Goto et al. (2010); Hendron et al. (2014)
		Inhibitor-high contration	Goto et al. (2010); Hendron et al. (2014)
BTP2	SOCE	Inhibitor	Ishikawa et al. (2003)
	CRAC	Inhibitor	Zitt et al. (2004)
	TRPC1	Inhibitor	Oláh et al. (2011)
	TRPC6	Inhibitor	Wu et al. (2017)
	TRPC3	Inhibitor	He et al. (2005)
	TRPC5	Inhibitor	He et al. (2005)
	TRPM4	Activator	Takezawa et al. (2006)
Pyr3	SOCE	Inhibitor	Schleifer et al. (2012)
	TRPC3	Inhibitor	Kiyonaka et al. (2009); Oda et al. (2017); Wang et al. (2019)
Pyr6	SOCE	Inhibitor	Schleifer et al. (2012); Chauvet et al. (2016)
	TRPC3	Inhibitor	Schleifer et al. (2012); Chauvet et al. (2016)
Pyr10	TRPC3	Inhibitor	Schleifer et al. (2012)
GSK (GSK-5503A/GSK-7975A/GSK-5498A)	SOCE	Inhibitor	Yamashita et al. (2007); Derler et al. (2013); Jairaman and Prakriya (2013); Rice et al. (2013); Chen and Sanderson (2017)
	TRPV6	Inhibitor	Owsianik et al. (2006); Jairaman and Prakriya (2013)
Synta66	SOCE	Specific inhibitor	Li et al. (2011)
mAbs	Orai1	Inhibitor	Cox et al. (2013); Lin et al. (2013)
CAI	SOCE	Inhibitor	Sjaastad et al. (1996)
	RMCE	Inhibitor	Hupe et al. (1991); Kohn et al. (1994)
	VDCE	Inhibitor	Hupe et al. (1991); Kohn et al. (1994)
RP4010	SOCE	Inhibitor	Cui et al. (2018)
CM4620	SOCE	Inhibitor	Wen et al. (2015)
ML-9	Myosin light chain kinases	Inhibitor	Saitoh et al. (1987)
	SOCE	Inhibitor	Smyth et al. (2008); Cui et al. (2017)
	CRAC	Inhibitor	Smyth et al. (2008)
	TRPC5	Inhibitor	Shimizu et al. (2006)
NPPB	CCE	Inhibitor	Gericke et al. (1994)
	CRAC	Inhibitor	Li et al. (2000)
AnCoA4	SOCE	Inhibitor	Sadaghiani et al. (2014)
RO2959	SOCE	Inhibitor	Chen G. et al. (2013)
YZ129	NFAT	Inhibitor	Liu et al. (2019)
MRS-1844/MRS-1845	SOCE	Inhibitor	Harper et al. (2003); van Kruchten et al. (2012)
	L-type channels	Inhibitor	Harper et al. (2003)
DES	SOCE	Inhibitor	Zakharov et al. (2004); Ohana et al. (2009); Dobrydneva et al. (2010)
NSAIDs	SOCE	Inhibitor	Núñez et al. (2006)
Mibefradil	SOCE	Inhibitor	Li et al. (2019)