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. 2021 May 28;12:685473. doi: 10.3389/fphys.2021.685473

TABLE 2.

All parameters recorded before (PRE) and at the end of head down tilt bed rest (HDT), sorted by intervention: control (Ctr), continuous artificial gravity (cAG) and intermittent artificial gravity (iAG).

Parameter Ctr (n = 8, 2 women)
cAG (n = 8, 3 women)
iAG (n = 8, 3 women)
p-values
PRE HDT PRE HDT PRE HDT Main effect Interaction
Aortic SBP (mmHg) 112 ± 10 113 ± 8 109 ± 17 108 ± 7 104 ± 7 105 ± 5 0.116 0.463
Aortic DBP (mmHg) 73 ± 9 82 ± 10 72 ± 7 81 ± 5 70 ± 7 79 ± 3 0.680 0.803
SBP (mmHg) 125 ± 8 129 ± 8 127 ± 15 124 ± 11 123 ± 10 120 ± 6 0.542 0.050
DBP (mmHg) 71 ± 8 80 ± 10 70 ± 6 79 ± 5 68 ± 8 76 ± 3 0.532 0.921
Pulse pressure (mmHg) 54 ± 8 49 ± 10 57 ± 15 45 ± 9 55 ± 15 44 ± 7 0.773 0.112
Heart rate (bpm) 62 ± 8 70 ± 10 63 ± 12 71 ± 15 62 ± 7 65 ± 10 0.710 0.162
Stroke volume (ml) 99 ± 27 84 ± 12 94 ± 21 78 ± 11 99 ± 14 87 ± 20 0.683 0.712
Cardiac output (l/min) 6.0 ± 1.3 5.9 ± 0.9 5.7 ± 0.7 5.5 ± 1.0 6.0 ± 0.8 5.6 ± 1.5 0.859 0.706
PATArm (ms) 160 ± 14 173 ± 19 153 ± 14 160 ± 14 149 ± 16 156 ± 15 0.125 0.993
PATFinger (ms) 209 ± 15 214 ± 17 208 ± 22 198 ± 19 199 ± 15 201 ± 13 0.390 0.582
PATThigh (ms) 215 ± 14 222 ± 17 205 ± 19 208 ± 18 208 ± 24 221 ± 22 0.188 0.376
PATToe (ms) 349 ± 17 354 ± 29 360 ± 26 347 ± 26 349 ± 23 350 ± 21 0.716 0.443
ICT (ms) 50 ± 10 63 ± 12 50 ± 7 54 ± 11 47 ± 6 54 ± 9 0.307 0.445
cPATArm (ms) 110 ± 14 110 ± 18 103 ± 15 106 ± 14 101 ± 14 103 ± 12 0.218 0.410
cPATFinger (ms) 159 ± 16 151 ± 11 158 ± 22 145 ± 18 151 ± 10 147 ± 9 0.811 0.447
cPATThigh (ms) 165 ± 16 160 ± 11 155 ± 20 154 ± 16 161 ± 22 167 ± 22 0.343 0.063
cPATToe (ms) 300 ± 12 291 ± 25 310 ± 21 290 ± 23 301 ± 21 297 ± 22 0.555 0.405
bfPWV (m/s) 9.0 ± 1.1 9.2 ± 1.5 9.1 ± 1.0 9.5 ± 0.8 9.0 ± 1.5 9.0 ± 1.6 0.664 0.875
AOC (ml/mmHg) 2.6 ± 0.6 2.8 ± 0.2 2.8 ± 0.7 3.0 ± 0.5 2.9 ± 0.3 3.4 ± 0.7 0.176 0.386
AOD (10–3 mm Hg–1) 5.2 ± 2.4 4.4 ± 2.9 4.7 ± 2.1 4.5 ± 1.9 4.6 ± 1.7 4.1 ± 1.9 0.465 0.865
AOAmin (mm2) 496 ± 70 504 ± 107 456 ± 79 487 ± 52 492 ± 116 522 ± 138 0.630 0.317

Aortic SBP and aortic DBP, aortic systolic and diastolic blood pressure; SBP and DBP, brachial systolic and diastolic blood pressure; PAT, pulse wave arrival time; ICT, isovolumetric contraction time; cPAT, PAT corrected for ICT; bfPWV, brachial-femoral pulse wave velocity; AOC, aortic compliance; AOD, aortic distensibility; AOAmin, minimum aortic area. Each parameter is represented as mean value ± standard deviation together with p-values for main effects (intervention) and interaction (intervention vs. bed rest).