TABLE 3.
All parameters recorded before (PRE) and at the end of head down tilt bed rest (HDT).
| AgeGr. 1 (n = 9, 2 Women) |
AgeGr. 2 (n = 8, 4 Women) |
AgeGr. 3 (n = 7, 2 Women) |
p-values |
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| PRE | HDT | PRE | HDT | PRE | HDT | Main effect | Interaction | |
| Aortic SBP (mmHg) | 104 ± 7 | 110 ± 9 | 104 ± 8 | 103 ± 4 | 119 ± 14 | 113 ± 5 | 0.004 | 0.070 |
| Aortic DBP (mmHg) | 69 ± 6 | 82 ± 8 | 72 ± 5 | 79 ± 4 | 75 ± 10 | 82 ± 7 | 0.538 | 0.096 |
| SBP (mmHg) | 122 ± 12† | 127 ± 10 | 122 ± 8 | 118 ± 7 | 133 ± 11† | 127 ± 7 | 0.071 | 0.009 |
| DBP (mmHg) | 67 ± 6 | 80 ± 9 | 70 ± 4 | 76 ± 4 | 73 ± 11 | 79 ± 8 | 0.569 | 0.144 |
| Pulse pressure (mmHg) | 55 ± 13 | 48 ± 9 | 52 ± 10 | 42 ± 5 | 60 ± 15 | 48 ± 11 | 0.527 | 0.217 |
| Heart rate (bpm) | 59 ± 6‡ | 70 ± 10 | 68 ± 11 | 70 ± 14 | 60 ± 7 | 65 ± 11 | 0.665 | 0.047 |
| Stroke volume (ml) | 108 ± 21 | 84 ± 17 | 83 ± 19 | 74 ± 11 | 100 ± 11 | 91 ± 13 | 0.129 | 0.093 |
| Cardiac output (l/min) | 6.3 ± 1.2 | 5.9 ± 1.4 | 5.5 ± 0.7 | 5.2 ± 1.0 | 5.9 ± 0.3 | 5.9 ± 0.7 | 0.572 | 0.830 |
| PATArm (ms) | 161 ± 15 | 163 ± 18 | 154 ± 10† | 162 ± 11 | 144 ± 15† | 164 ± 23 | 0.441 | 0.014 |
| PATFinger (ms) | 212 ± 16 | 201 ± 20 | 205 ± 21 | 202 ± 15 | 198 ± 14 | 211 ± 18 | 0.978 | 0.095 |
| PATThigh (ms) | 220 ± 18 | 222 ± 21 | 208 ± 15 | 212 ± 16 | 198 ± 19 | 216 ± 22 | 0.158 | 0.086 |
| PATToe (ms) | 351 ± 21 | 342 ± 22 | 357 ± 18 | 359 ± 17 | 349 ± 29 | 353 ± 32 | 0.167 | 0.567 |
| ICT (ms) | 46 ± 7 | 59 ± 10 | 52 ± 8 | 52 ± 13 | 50 ± 7 | 59 ± 9 | 0.849 | 0.187 |
| cPATArm (ms) | 115 ± 13† | 104 ± 11 | 102 ± 10 | 110 ± 13 | 94 ± 11† | 106 ± 21 | 0.203 | 0.001 |
| cPATFinger (ms) | 166 ± 15‡ | 142 ± 15 | 153 ± 20 | 150 ± 13 | 148 ± 9 | 153 ± 8 | 0.828 | 0.004 |
| cPATThigh (ms) | 173 ± 16† | 163 ± 18 | 157 ± 15 | 161 ± 19 | 148 ± 18† | 157 ± 17 | 0.057 | 0.006 |
| cPATToe (ms) | 305 ± 19 | 282 ± 19 | 305 ± 14 | 304 ± 19 | 300 ± 24 | 294 ± 26 | 0.192 | 0.105 |
| bfPWV (m/s) | 8.5 ± 0.5 | 8.7 ± 0.8 | 9.1 ± 1.0 | 9.6 ± 1.5 | 9.7 ± 1.7 | 9.4 ± 1.5 | 0.013 | 0.219 |
| AOC (ml/mmHg) | 3.1 ± 0.5 | 3.1 ± 0.8 | 2.6 ± 0.5 | 3.1 ± 0.5 | 2.3 ± 0.4 | 2.9 ± 0.3 | 0.448 | 0.163 |
| AOD (10–3 mm Hg–1) | 5.3 ± 1.6 | 4.6 ± 2.6 | 5.4 ± 2.5 | 5.1 ± 2.2 | 3.6 ± 1.3 | 3.1 ± 1.0 | 0.053 | 0.937 |
| AOAmin (mm2) | 417 ± 46 | 441 ± 69 | 497 ± 62 | 497 ± 65 | 547 ± 105 | 595 ± 113 | 0.027 | 0.139 |
Results are sorted by three different age groups (AgeGr): AgeGr. 1, 24–27 years; AgeGr. 2, 29–36 years and AgeGr. 3, 37–55 years. Aortic SBP and aortic DBP, aortic systolic and diastolic blood pressure; SBP and DBP, brachial systolic and diastolic blood pressure; PAT, pulse wave arrival time; ICT, isovolumetric contraction time; cPAT, PAT corrected for ICT; bfPWV, brachial-femoral pulse wave velocity; AOC, aortic compliance; AOD, aortic distensibility; AOAmin, minimum aortic area. Results are represented as mean values ± standard deviation. Statistical significance (p < 0.05) for main effect (AgeGr.) and interaction (AgeGr. vs. bed rest) is indicated by p-values in bold. Significant difference between PRE and HDT is indicated by †(p < 0.05) and ‡(p < 0.001).