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. 2021 May 28;12:685473. doi: 10.3389/fphys.2021.685473

TABLE 4.

All parameters recorded before (PRE) and at the end of head down tilt bed rest (HDT).

Parameter Men (n = 16)
Women (n = 8)
p-values
PRE HDT PRE HDT Main effect Interaction
Aortic SBP (mmHg) 111 ± 12 111 ± 7 102 ± 8 103 ± 5 0.017 0.439
Aortic DBP (mmHg) 70 ± 8 81 ± 8 75 ± 5 80 ± 4 0.394 0.109
SBP (mmHg) 129 ± 10 128 ± 7 117 ± 8 116 ± 6 0.001 0.389
DBP (mmHg) 68 ± 8 79 ± 8 73 ± 5 78 ± 4 0.278 0.157
Pulse pressure (mmHg) 61 ± 11 50 ± 8 44 ± 4 38 ± 3 <0.001 0.071
Heart rate (bpm) 58 ± 5 66 ± 11 70 ± 9 74 ± 12 0.022 0.614
Stroke volume (ml) 107 ± 17 89 ± 13 78 ± 12 71 ± 11 0.001 0.289
Cardiac output (l/min) 6.1 ± 1.0 5.9 ± 1.1 5.4 ± 0.5 5.2 ± 1.0 0.243 0.726
PATArm (ms) 155 ± 17 167 ± 19 15 ± 19 155 ± 10 0.274 0.090
PATFinger (ms) 209 ± 20 208 ± 18 199 ± 11 198 ± 15 0.257 0.981
PATThigh (ms) 215 ± 20 223 ± 19 199 ± 12 205 ± 17 0.050 0.732
PATToe (ms) 353 ± 23 352 ± 25 350 ± 22 346 ± 24 0.181 0.910
ICT (ms) 48 ± 7 58 ± 11 52 ± 7 54 ± 12 0.958 0.328
cPATArm (ms) 108 ± 16 109 ± 17 98 ± 7 101 ± 7 0.177 0.588
cPATFinger (ms) 161 ± 18 150 ± 14 147 ± 11 144 ± 9 0.131 0.438
cPATThigh (ms) 167 ± 19 164 ± 17 147 ± 12 152 ± 16 0.024 0.567
cPATToe (ms) 306 ± 18 294 ± 24 298 ± 20 290 ± 20 0.115 0.405
bfPWV (m/s) 8.6 ± 0.6 9.0 ± 1.2 9.9 ± 1.6 9.7 ± 1.4 0.016 0.161
AOC (ml/mmHg) 2.7 ± 0.6 3.1 ± 0.6 2.9 ± 0.4 3.0 ± 0.4 0.588 0.304
AOD (10–3 mm Hg–1) 4.8 ± 2.0 4.4 ± 2.3 4.8 ± 2.1 4.1 ± 2.1 0.705 0.740
AOAmin (mm2) 486 ± 97 512 ± 112 471 ± 73 490 ± 82 0.384 0.879

Aortic SBP and aortic DBP, aortic systolic and diastolic blood pressure; SBP and DBP, brachial systolic and diastolic blood pressure; PAT, pulse wave arrival time; ICT, isovolumetric contraction time; cPAT, PAT corrected for ICT; bfPWV, brachial-femoral pulse wave velocity; AOC, aortic compliance; AOD, aortic distensibility; AOAmin, minimum aortic area. Results are sorted by sex and represented as mean values ± standard deviation. Statistical significance (p < 0.05) for main effect (sex) and interaction (sex vs. bed rest) is indicated by bold p-values.