TABLE 6.

Per-residue energy contribution of five key residues obtained through ANCHOR analysis for equilibrated simulation trajectory of C-Raf/RKIP structural complex.

C-raf		RKIP
Residues	Binding free energy (kcal/mol)	Residues	Binding free energy (kcal/mol)
Arg398	−12.8	Lys80	−15.9
Lys399	−9.9	Gly186	−12.1
Glu345	−8.9	Glu182	−10.4
Glu348	−6.4	Lys148	−1.6
Tyr340	−5.8	Tyr181	−1.4

*Majorly contributing residues highlighted in bold.