Table 1.

Patient characteristics

Patient no.	Sex	Tested negative	Age (years)		Location of primary	Hypersecretion	Time to metastasis (years)	Location of metastases
			Diagnosis	Time of study
1	m	SDHx, VHL	61	75	Right adrenal	NM, NE, DA, CgA	12	A/P
2	f	SDHx	52	55	Left adrenal	NM, NE, CgA	3	A/P, B
3	f	SDHx	54	54	Left para-adrenal	NM, NE, CgA	0	A/P, B
4	m	SDHx, MEN, VHL, TMEM 127	20	37	Right para-adrenal	NM	0	A/P, B, Li, Lu
5	m	SDHx, MEN, VHL	27	30	Unknown	NE, NM, DA, CgA	0	A/P, B, Li, Me
6	f	SDHx	21	46	Right glomus jugulare	None	9	A/P, B, Me, Ne
7	f	SDHx, MEN, VHL, MAX, TMEM 127	52	64	Left adrenal	NM, NE, DA, MTT, CgA	6	A/P, B, Li, Lu
8	f	SDHx, MAX	38	47	Left adrenal	NM, MN, CgA	7	B
9	f	SDHx	12	31	Left para-adrenal	CgA,	4	A/P, B, Lu
10	m	SDHx	56	59	Right adrenal	NM, MN, NE, DA, CgA	0	A/P, B, Lu, Ne
11	m	SDHx	42	52	Unknown	DA, CgA, MTT	5	A/P, B, Lu, Me, Ne
12	m	SDHx	49	52	Right retroperitoneal	CgA	0	B, Li
13	m	SDHx, VHL	54	61	Left adrenal	NM, NE, CgA, DA	0	A/P, B, Li, Lu, Me
14	m	SDHx, MAX	70	73	Left adrenal	NM, NE, CgA, DA	0	A/P, Lu, Me
15	m	SDHx	34	35	Left retroperitoneal	NM, NE, MN, Epi, DA, CgA	0	A/P, B, Li, Lu
16	m	SDHx	31	43	Right adrenal	NM, NE, DA, CgA	6	A/P, B, Me
17	m	SDHx, VHL	23	25	Right adrenal	NM, NE, DA, CgA, MTT	0	A/P, B, Li, Lu
18	m	SDHx	38	39	Right para-adrenal	NM, CgA	0	A/P, B, Li, Me
19	m	SDHx	43	64	Right adrenal	NM, NE, MN, Epi, DA, CgA, MTT	15	A/P, B
20	m	SDHx	34	41	Left adrenal	MTT	5	A/P, B
21	f	SDHx	63	64	Left adrenal	NM, NE, Epi, CgA, MTT	0	B, Li
22	m	SDHx	37	39	Right adrenal	NM, DA	2	B, Li, Lu

A/P abdominal/pelvic compartment, B bones, CgA chromogranin A, DA dopamine, Epi epinephrine, Li liver, Lu lungs, m male, MAX myc-associated factor X, Me mediastinum, MTT methoxytyramine, Ne neck, NE norepinephrine, NM normetanephrine, TMEM 127 trans-membrane protein 127