TABLE 5.
Multivariate Cox proportional hazards regression analysis of NLR and PLR with progression-free survival.
| Characteristic | B | SE B | Wald | HR | 95% CI | p value | |
|---|---|---|---|---|---|---|---|
| NLR | |||||||
| Tumor size (cm) | >5/≤5 | 0.303 | 0.123 | 6.091 | 1.354 | 1.064–1.722 | 0.014 |
| AST (U/L) | >40/≤40 | 0.378 | 0.121 | 9.712 | 1.459 | 1.151–1.850 | 0.002 |
| Extrahepatic spread | Yes/no | 0.378 | 0.121 | 9.712 | 1.459 | 1.151–1.850 | 0.002 |
| NLR | ≥2.42/<2.42 | 0.246 | 0.123 | 4.013 | 1.278 | 1.005–1.626 | 0.045 |
| PLR | |||||||
| Tumor size (cm) | >5/≤5 | 0.271 | 0.123 | 4.865 | 1.312 | 1.031–1.669 | 0.027 |
| AST (U/L) | >40/≤40 | 0.390 | 0.120 | 10.643 | 1.477 | 1.169–1.868 | 0.001 |
| Extrahepatic spread | Yes/no | 0.735 | 0.193 | 14.500 | 2.086 | 1.429–3.045 | <0.001 |
| PLR | ≥100/<100 | 0.345 | 0.122 | 8.063 | 1.412 | 1.113–1.792 | 0.005 |
AST, aspartate transaminase; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; SE, standard error; CI, confidence interval; HR, hazard ratio.