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. 2020 Dec 7;320(1):E150–E159. doi: 10.1152/ajpendo.00161.2020

Figure 3.

Figure 3.

Myostatin deficiency inhibited sepsis-induced decrease in gastrocnemius muscle fiber cross-sectional area in mice. A: the cross-sectional area of gastrocnemius muscle fibers was greater in myostatin-deficient (MSTN) mice than in body weight-matched wild-type (WT) mice prior to and at 14 days after CLP. Scale bar: 50 μm. *P < 0.05, **P < 0.01 vs. WT without CLP, †††P < 0.001 vs. WT mice with CLP, §P < 0.05 vs. MSTN without CLP. B: the cecum ligation and puncture (CLP)-induced percent decreases in cross-sectional area of gastrocnemius muscle fibers were less in myostatin-deficient (MSTN) mice than in body weight-matched wild-type (WT) mice. *P < 0.05 vs. WT mice, WT without CLP: n = 4, WT mice with CLP: n = 4, MSTN without CLP: n = 6, MSTN mice with CLP: n = 6.