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. 2021 May 20:bbab192. doi: 10.1093/bib/bbab192

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© The Author(s) 2021. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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Comparison of variable (V) and joining (J) gene usage in BCR heavy chain between COVID-19 patients and healthy controls. (A) The proportion of each IGHV gene in COVID-19 patients (red) and healthy controls (green). (B–E) The differential analysis of IGHV2 (b), IGHV3(c), IGHV4 (d) and IGHV1 (e) gene family by Fisher’s exact test, the red dots represent P < 0.05 and the grey dots represent P > 0.05. (F) The same barplot as (A) for the IGHJ gene. (G) The differential analysis of IGHJ gene by Fisher’s exact test.