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. 2021 May 28;14:639145. doi: 10.3389/fnmol.2021.639145

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Copyright © 2021 Kuo, Wang, Wu, Chen and Tseng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Time course of microglia/macrophage activation after cortical stroke. Representative images of TTC staining and immunostaining of all microglia/macrophages (CD11b) from ischemic core (IC), peri-infarct area, and hippocampus (Hip) coronal sections at 1 (A,B), 2 (C,D), and 7 (E,F) days after 90-min dMCAo in rats. The morphological changes and increasing number of microglia/macrophages were obviously found at 2 days after ischemia. Scale bar is 50 μm (immunofluorescence of CD11b) and 5000 μm (TTC staining).