FIGURE 1.
Increased ACE2 levels and activity amongst COVID-19 patients with a smoking history. (A) Blood serum samples from COVID-19 negative (CoV–) and COVID-19 (positive and recovered) patients were obtained and the ACE2 level was quantitatively measured. ∗p < 0.05 as per Mann Whitney’s test for pairwise comparisons. CoV+: COVID19 positive (current and recovered) patients. (B) Patient Sera from healthy (CoV–), COVID-19 positive (CoV+), and COVID-19 recovered (CoV Rec) subjects were obtained, and ACE2 Activity was quantitatively measured. The obtained results were plotted based on serum ACE2 activity in (i) healthy subjects vs. COVID-19 positive and COVID-19 recovered patients. Data are shown as mean ± SEM. (∗∗∗p < 0.001, as per one-way ANOVA for multiple comparisons), (ii) COVID-19 (positive and recovered) patients with or without a smoking history, and (iii) COVID-19 patients based on their gender. Data are shown as mean ± SEM. ∗p < 0.05, ∗∗∗ p < 0.001 as per unpaired t-test.
